Yes … https://doc.e.foundation/what-s-e#degoogling–ungoogling.
Yes … Uninstall default apps - #29 by AnotherElk.
Uninstall … I’m not sure how /e/ would behave then, but supposedly you can … /e/ pre-installed Grade A smartphones : How to buy them - #45 by archje.
Deactivate … you can deactivate its components in the microG settings.
Anyway, if you and your Apps don’t use it, microG does no harm just by being there.