Running Protonmail and ProtonVPN

Has anyone had any conflicts using these two services with Murena One? Do they conflict with the Advance Privacy? Are they a better alternative to /e/ privacy?

The system generally provides only one single vpn-interface.
Therefore you cannot use APs hide my ip when you use any “real” or “external” vpn service like proton or else … In this specific case it’s either- or.